Biography

An active area of research in the Johnston laboratory consists of the delivery of biologically-active small peptide drugs via the paracellular route following oral dosing. On a totally different front, we have developed a mouse model of dyslipidemia and atherosclerosis and are presently determining convenient biomarkers (oxidized-LDL-cholesterol, cell adhesion molecules, PPARs, “dysfunctional” HDL-cholesterol, etc.) that may be used to predict patients at risk for future coronary artery disease.